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Dimethoxypropane hydrobenzoin acetonide3/11/2024 ![]() Clean up: The aqueous solutions from washing steps can be diluted solutions from washing steps can be diluted with water and drained into the sink. Which diastereomer (meso or (+)) is the major product of the benzil reduction with borohydride? What is the ratio of the major product to the minor one? Explain the stereoselectivity of the borohydride reduction. When the crystals are dry weigh your product, measure mp and submit sample for NMR analysis (1 sample/section). Filter the solution into a clean dry Erlenmeyer flask and let the solvent evaporate, Evaporation of the solvent yields the crude product. Separate the organic layer and dry it over Na2SO4 for at least 10 min. Wash the organic phase successively with H2O (10 mL) and saturated NaHCO, (10 mL) (organic layer will be on the bottom). ![]() Add CH CL (15 mL) to the reaction mixture and transfer solution into a small se flask with additional CH2CL (10 ml) and place it in the separatory funnel as well. Cork the flask and stir the ((5 mg - one-two crystals) and a magnet bar into 25 mL Erlenmeyer flack mixture at room temperature for 1 hour. Transcribed image text: Experimental Section: O Place hydrobenzoin (200 mg), 2,2-dimethoxypropane (2.5 mL), P-tolu 2.2-dimethoxypropane (2.5 mL), P-toluenesulfonic acid monohydrate a magnet bar into 25 mL Erlenmeyer flask.
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